Differential diagnosis
- Endometrial Ca – IMB, PCB, weight loss
- Ovarian Ca – weight loss, bowel habit changes, abdominal distension, early satiety, pelvic pain
- Infection – fever, PV discharge, change in partner
- Fibroids – bloating, pressure symptoms (bladder, bowel)
- Others – thyroid disease, coagulation disease, liver disease
- Dysfunctional uterine bleeding – if above ruled out
Data gathering
- Red flags – sudden onset, IMB, PCB, last smear
- Others – pads, clots, flooding, abdo pain, SOB/palpitations/lethargy, PV discharge, contraception, pregnancies
- Examine – abdomen, pelvis, speculum
Clinical management
- Investigations
- Bloods – FBC, TFTs
- Swabs – vaginal, endocervical
- Cervical smear (if due)
- USS Pelvis
- Explanation
- many causes, changes in hormones, fibroids (benign growths), endometriosis (womb lining grows outside of the womb)
- Treatment
- Menstrual diary
- Medications
- Tranexamic acid 1g TDS from day 1 of cycle for four days
- Mefenamic acid 500mg TDS (if associated dysmenorrhoea)
- Mirena coil
- COCP / depot injection
- Norethisterone 5mg TDS day 5 – 26
- Follow-up / Safety net
- Consider referral if failed treatment or secondary anaemia.
- Gynae can offer endometrial ablation, hysterectomy