| Condition | Notes |
|---|---|
| Liver disease | History of alcohol excess Stigmata of chronic liver disease: spider naevi, bruising, palmar erythema, gynaecomastia etc Evidence of decompensation: ascites, jaundice, encephalopathy |
| Iron deficiency anaemia | Pallor Other signs: koilonychia, atrophic glossitis, post-cricoid webs, angular stomatitis |
| Polycythaemia | Pruritus particularly after warm bath ‘Ruddy complexion’ Gout Peptic ulcer disease |
| Chronic kidney disease | Lethargy & pallor Oedema & weight gain Hypertension |
| Lymphoma | Night sweats Lymphadenopathy Splenomegaly, hepatomegaly Fatigue |
| Hyper- and hypothyroidism | |
| Diabetes | |
| Pregnancy | |
| Senile pruritus | |
| Urticaria | |
| Skin disorders | Eczema, scabies, psorasis, pityriasis rosea |