Lymphocytes

Raised lymphocytes

  • If features of viral illness and otherwise well – repeat in 4 weeks
  • Causes
    • Infection – EBV, CMV, Pertussis, Mumps, Rubella, Stress
    • Vigorous exercise
    • Post splenectomy
    • Haematological malignancies – ALL, CLL, NHL
  • Refer
    • 20 x 109/L
    • Lymphadenopathy
    • Splenomegaly
    • Other cytopenia
    • Weight loss
    • Night sweats
    • Pyrexia unknown origin
    • Persistent

 

Reduced lymphocytes

  • Causes
    • Medications – steroids
    • Infection – post viral, HIV, Legionella
    • Malignancy – marrow infiltration, myeloma, post chemoradiotherapy
    • Renal/Hepatic impairment
    • Connective tissue disease – RA, SLE, Sarcoid
    • Anorexia Nervosa
    • Primary immune deficiency
  • Refer
    • Persistent