{"id":49,"date":"2017-03-22T20:22:08","date_gmt":"2017-03-22T20:22:07","guid":{"rendered":"http:\/\/papergp.com\/index.php\/cystic-fibrosis\/"},"modified":"2017-07-17T19:33:44","modified_gmt":"2017-07-17T19:33:44","slug":"cystic-fibrosis","status":"publish","type":"page","link":"https:\/\/papergp.com\/index.php\/others\/genetics\/cystic-fibrosis\/","title":{"rendered":"Cystic fibrosis"},"content":{"rendered":"<h5><b>Background:<\/b><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">Autosomal recessive disease &#8211; affecting lungs, pancreas, GI system<\/span><\/h5>\n<h5><span style=\"font-weight: 400;\">Recurrent chest infections, failure to thrive, malabsorption<\/span><\/h5>\n<h5><span style=\"font-weight: 400;\">1\/25 Caucasian people are carriers<\/span><\/h5>\n<h5><b>Data gathering<\/b><\/h5>\n<h5><b>Clinical management<\/b><\/h5>\n<h5><span style=\"font-weight: 400;\">Genetic testing of parents &#8211; blood test or mouth scrapings<\/span><\/h5>\n<h5><span style=\"font-weight: 400;\">Antenatal testing &#8211; CVS (10-13 weeks), only for those at high risk<\/span><\/h5>\n<h5><span style=\"font-weight: 400;\">After birth testing &#8211; heel prick on day 5, sweat test if older<\/span><\/h5>\n<h5><span style=\"font-weight: 400;\">Explanation &#8211; two CF genes need to be inherited, the CF gene is responsible for how cells handle salt, water, mucus so mucus ends up being thicker than normal and the body has trouble clearing this from the body hence digestive and lung problems<\/span><\/h5>\n<h5><span style=\"font-weight: 400;\">If both parents have CF gene, refer for genetic counselling<\/span><\/h5>\n<h5><span style=\"font-weight: 400;\">PIL<\/span><\/h5>\n","protected":false},"excerpt":{"rendered":"<p>Background: Autosomal recessive disease &#8211; affecting lungs, pancreas, GI system Recurrent chest infections, failure to thrive, malabsorption 1\/25 Caucasian people are carriers Data gathering Clinical management Genetic testing of parents &#8211; blood test or mouth scrapings Antenatal testing &#8211; CVS (10-13 weeks), only for those at high risk After birth testing &#8211; heel prick on &hellip; <a href=\"https:\/\/papergp.com\/index.php\/others\/genetics\/cystic-fibrosis\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Cystic fibrosis<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":43,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-49","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/49","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/comments?post=49"}],"version-history":[{"count":2,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/49\/revisions"}],"predecessor-version":[{"id":64,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/49\/revisions\/64"}],"up":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/43"}],"wp:attachment":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/media?parent=49"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}