{"id":1329,"date":"2017-06-27T16:17:06","date_gmt":"2017-06-27T16:17:06","guid":{"rendered":"http:\/\/papergp.com\/index.php\/data-interpretation\/fbc-2\/neutrophils\/"},"modified":"2023-01-24T11:25:25","modified_gmt":"2023-01-24T11:25:25","slug":"neutrophils","status":"publish","type":"page","link":"https:\/\/papergp.com\/index.php\/data-interpretation\/fbc-2\/neutrophils\/","title":{"rendered":"Neutrophils"},"content":{"rendered":"<div class=\"content-box-blue\">\n<h4>Low neutrophils<\/h4>\n<ul>\n<li>Causes\n<ul>\n<li>Infection &#8211; EBV, HBV, HCV, HIV<\/li>\n<li>Ethnic variation &#8211; Afro-Carribean, SE Asian<\/li>\n<li>Medications &#8211; Phenytoin, Carbimazole, Antipsychotics, Clotrimoxazole<\/li>\n<li>Endocrine &#8211; Thyroid<\/li>\n<li>Malignancy &#8211; marrow infiltration, myeloma, post chemoradiotherapy<\/li>\n<li>Connective tissue disease &#8211; RA, Gout<\/li>\n<li>Autoimmune disease<\/li>\n<li>Deficiency &#8211; B12, Folate, Iron<\/li>\n<li>Alcohol excess<\/li>\n<li>Liver disease &#8211; Cirrhosis<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul>\n<li>Assess severity\n<ul>\n<li>1-1.5 x 109\/L\n<ul>\n<li>Bloods: FBC\/blood film, B12, folate, ferritin, ANA<\/li>\n<li>Repeat in 4 weeks<\/li>\n<li>Refer\n<ul>\n<li>Persistent<\/li>\n<li>Other FBC abnormalities<\/li>\n<li>Recurrent infections\/ulcers<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<li>&lt;1 x 109\/L\n<ul>\n<li>Well and afebrile\n<ul>\n<li>Bloods: FBC\/blood film, B12, folate, ferritin, ANA<\/li>\n<li>Repeat in 1 week<\/li>\n<li>Refer\n<ul>\n<li>Persistent<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<li>Unwell, febrile, chemotherapy, lymphadenopathy, splenomegaly, other cytopenia\n<ul>\n<li>Emergency referral<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<p>&nbsp;<\/p>\n<div class=\"content-box-blue\">\n<h4>Raised neutrophils<\/h4>\n<ul>\n<li>Causes\n<ul>\n<li>Infection &#8211; bacterial, some viral (VZV, HSV), fungal, parasitic<\/li>\n<li>Medications &#8211; steroids<\/li>\n<li>Malignancy &#8211; carcinoma, lymphoma, leukaemia<\/li>\n<li>Connective Tissue Disease &#8211; RA, Gout<\/li>\n<li>Haemorrhage, Haemolysis, Hypoxia, Infarction, Tissue damage<\/li>\n<\/ul>\n<\/li>\n<li>Repeat FBC in 4 weeks with inflammatory markers<\/li>\n<li>Refer\n<ul>\n<li>&gt;15 x 109\/L<\/li>\n<li>Splenomegaly<\/li>\n<li>Other FBC abnormalities<\/li>\n<li>Persistent<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Low neutrophils Causes Infection &#8211; EBV, HBV, HCV, HIV Ethnic variation &#8211; Afro-Carribean, SE Asian Medications &#8211; Phenytoin, Carbimazole, Antipsychotics, Clotrimoxazole Endocrine &#8211; Thyroid Malignancy &#8211; marrow infiltration, myeloma, post chemoradiotherapy Connective tissue disease &#8211; RA, Gout Autoimmune disease Deficiency &#8211; B12, Folate, Iron Alcohol excess Liver disease &#8211; Cirrhosis Assess severity 1-1.5 x 109\/L &hellip; <a href=\"https:\/\/papergp.com\/index.php\/data-interpretation\/fbc-2\/neutrophils\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Neutrophils<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1301,"menu_order":7,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1329","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1329","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/comments?post=1329"}],"version-history":[{"count":4,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1329\/revisions"}],"predecessor-version":[{"id":2067,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1329\/revisions\/2067"}],"up":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1301"}],"wp:attachment":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/media?parent=1329"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}