{"id":1305,"date":"2017-06-24T19:03:41","date_gmt":"2017-06-24T19:03:41","guid":{"rendered":"http:\/\/papergp.com\/index.php\/data-interpretation\/fbc-2\/polycythaemia\/"},"modified":"2023-01-24T11:25:25","modified_gmt":"2023-01-24T11:25:25","slug":"polycythaemia","status":"publish","type":"page","link":"https:\/\/papergp.com\/index.php\/data-interpretation\/fbc-2\/polycythaemia\/","title":{"rendered":"Polycythaemia"},"content":{"rendered":"<div class=\"content-box-blue\">\n<h4><strong>Background<\/strong><\/h4>\n<ul>\n<li>Men: Hb &gt; 185, Hct &gt; 0.52<\/li>\n<li>Women: Hb &gt; 160, Hct &gt; 0.48<\/li>\n<li>Causes of polycythaemia\n<ul>\n<li>Apparent\n<ul>\n<li>Reduced playsma volume<\/li>\n<li>Obesity, smoking, alcohol, hypertension, stress, dehydration diuretics<\/li>\n<\/ul>\n<\/li>\n<li>Absolute\n<ul>\n<li>Polycythaemia Rubra Vera &#8211; 90% are JAK2 positive<\/li>\n<li>Secondary polycythaemia &#8211; hypoxia (COPD, heart disease, smoking) \/ abnormal EPO production (renal\/ liver tumours, fibroids)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<p>&nbsp;<\/p>\n<div class=\"content-box-blue\">\n<h4><strong>Assess<\/strong><\/h4>\n<ul>\n<li>Assess WCC and platelets\n<ul>\n<li>WCC and platelets normal\n<ul>\n<li>Probable secondary polycythaemia<\/li>\n<\/ul>\n<\/li>\n<li>WCC, platelets and basophils raised, ferritin low\n<ul>\n<li>Probable primary polycythaemia<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<p>&nbsp;<\/p>\n<div class=\"content-box-blue\">\n<h4><strong>Management<\/strong><\/h4>\n<ul>\n<li>History: Neurological symptoms, visual loss, bleeding, thrombosis<\/li>\n<li>Investigate: Monitor FBC, modify lifestyle factors, check<\/li>\n<li>Refer if\n<ul>\n<li>Hct &gt; 0.52 males + previous thrombosis, splenomegaly, pruritus, elevated WCC\/platelets<\/li>\n<li>Hct &gt; 0.48 females\u00a0+ previous thrombosis, splenomegaly, pruritus, elevated WCC\/platelets<\/li>\n<li>Persistent, unexplained raised Hct over 4 weeks apart<\/li>\n<\/ul>\n<\/li>\n<li>2 week referral\n<ul>\n<li>Hb \u00a0&gt;200 g\/l<\/li>\n<li>Hct &gt; 0.60 (in absence of chronic hypoxia)<\/li>\n<li>Raised Hb associated with thrombosis, neurological symptoms, visual loss, bleeding<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Background Men: Hb &gt; 185, Hct &gt; 0.52 Women: Hb &gt; 160, Hct &gt; 0.48 Causes of polycythaemia Apparent Reduced playsma volume Obesity, smoking, alcohol, hypertension, stress, dehydration diuretics Absolute Polycythaemia Rubra Vera &#8211; 90% are JAK2 positive Secondary polycythaemia &#8211; hypoxia (COPD, heart disease, smoking) \/ abnormal EPO production (renal\/ liver tumours, fibroids) &nbsp; &hellip; <a href=\"https:\/\/papergp.com\/index.php\/data-interpretation\/fbc-2\/polycythaemia\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Polycythaemia<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1301,"menu_order":6,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1305","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1305","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/comments?post=1305"}],"version-history":[{"count":4,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1305\/revisions"}],"predecessor-version":[{"id":1872,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1305\/revisions\/1872"}],"up":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1301"}],"wp:attachment":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/media?parent=1305"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}