{"id":1286,"date":"2017-06-22T18:16:10","date_gmt":"2017-06-22T18:16:10","guid":{"rendered":"http:\/\/papergp.com\/index.php\/data-interpretation\/lipids\/"},"modified":"2023-01-24T11:25:25","modified_gmt":"2023-01-24T11:25:25","slug":"lipids","status":"publish","type":"page","link":"https:\/\/papergp.com\/index.php\/data-interpretation\/lipids\/","title":{"rendered":"Lipids"},"content":{"rendered":"<div class=\"content-box-blue\">\n<h4>Data gathering<\/h4>\n<ul>\n<li>When to suspect familial hypercholesterolaemia\n<ul>\n<li>total cholesterol &gt; 7.5<\/li>\n<li>LDL &gt; 4.9<\/li>\n<li>premature heart disease\n<ul>\n<li>NB: QRISK2 underestimates in these groups<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<li>Triglycerides\n<ul>\n<li>4.5-9.9 mmol\/l &#8211; look at non-HDL cholesterol, refer if non-HDL is &gt; 7.5<\/li>\n<li>10-20 mmol\/l &#8211; repeat sample after fasting &#8211; if still elevated, seek advice (?alcohol, diabetess, hypothyroidism, liver disease, nephrotic syndrome)<\/li>\n<li>&gt;20 mmol\/L &#8211; refer<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<p>&nbsp;<\/p>\n<div class=\"content-box-blue\">\n<h4>Clinical management<\/h4>\n<ul>\n<li>Starting a statin\n<ul>\n<li>QRISK2 &gt; 10% &#8211; discuss statins with patient<\/li>\n<li>Atorvastatin 20mg &#8211; first line for primary prevention<\/li>\n<li>Atorvastatin 80mg &#8211; first line for secondary prevention<\/li>\n<li>Repeat LFTs in 3 months then 1 year\n<ul>\n<li>only stop if AT\/ALT &gt; 3x upper limit<\/li>\n<\/ul>\n<\/li>\n<li>Aim for 40 percent reduction in non-HDL cholesterol\n<ul>\n<li>total cholesterol minus HDL = Non-HDL cholesterol (not same as LDL)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<li>Refer\n<ul>\n<li>Total cholesterol &gt;9<\/li>\n<li>non HDL &gt; 7.5<\/li>\n<li>Triglycerides &gt; 20<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Data gathering When to suspect familial hypercholesterolaemia total cholesterol &gt; 7.5 LDL &gt; 4.9 premature heart disease NB: QRISK2 underestimates in these groups Triglycerides 4.5-9.9 mmol\/l &#8211; look at non-HDL cholesterol, refer if non-HDL is &gt; 7.5 10-20 mmol\/l &#8211; repeat sample after fasting &#8211; if still elevated, seek advice (?alcohol, diabetess, hypothyroidism, liver disease, &hellip; <a href=\"https:\/\/papergp.com\/index.php\/data-interpretation\/lipids\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Lipids<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1261,"menu_order":28,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1286","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1286","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/comments?post=1286"}],"version-history":[{"count":4,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1286\/revisions"}],"predecessor-version":[{"id":2084,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1286\/revisions\/2084"}],"up":[{"embeddable":true,"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/pages\/1261"}],"wp:attachment":[{"href":"https:\/\/papergp.com\/index.php\/wp-json\/wp\/v2\/media?parent=1286"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}